• RECTIV (nitroglycerin) Ointment 0.4% is a prescription medicine used to treat moderate to severe pain caused by chronic anal fissures
• RECTIV is not suitable for children and adolescents under the age of 18 years because it has not been studied in this age group

Important Safety Information

• Do not use RECTIV if you:
  • Are taking a medicine for erectile dysfunction (male impotence), such as Viagra^® (sildenafil), Cialis^® (tadalafil), or Levitra^® (vardenafil), or for pulmonary hypertension. If you have questions, consult your pharmacist or health care provider
  • Have been told by your doctor that you have severe anemia (low numbers of red blood cells)
  • Have increased intracranial pressure or high pressure within your skull (eg, following a head injury or bleeding in your brain)
  • Are allergic to any of the ingredients in RECTIV, or have had an allergic reaction to similar medications in the past
• Tell your doctor about all of your medical conditions including if you:
  • Have low blood pressure
  • Have recently had a heart attack
  • Have heart or blood vessel disorders
  • Suffer from migraines or recurrent headaches
  • Are pregnant or plan to become pregnant. It is not known if RECTIV or if the components of RECTIV will harm your unborn baby
  • Are breastfeeding or plan to breastfeed. It is not known if RECTIV or if the components of RECTIV will harm your child if you breastfeed
• RECTIV may lower your blood pressure. When getting up from a lying or sitting position, you should get up slowly, otherwise you might faint
• Tell your doctor about all the medicines you take, including prescription and nonprescription medicines, vitamins, and herbal supplements. Tell your doctor if you are taking other products that contain nitroglycerin, medicine for erectile dysfunction, certain medicines used for pulmonary hypertension, medicine used to treat high blood pressure, aspirin, ergotamine (used to treat migraine), tissue-type plasminogen activator (used to help dissolve blood clots in the heart, lungs, and brain), or are to be given heparin
• Do not drive or operate machinery immediately after applying RECTIV. If you feel dizzy or light-headed after applying the ointment, do not drive or operate machinery until the dizziness has stopped
• Avoid consuming alcohol while you are using RECTIV, as your blood pressure is more likely to be affected if you consume alcoholic beverages
• RECTIV can cause serious allergic reactions, including swelling of the face, lips, tongue, or throat, or difficulty breathing. If you have an allergic reaction, stop using RECTIV and seek immediate medical attention
• The most common side effects of RECTIV are:
  • Headaches, which can be severe. If you have a headache, you may take over-the-counter painkillers (such as acetaminophen), or ask your doctor whether you should stop taking RECTIV
  • Dizziness, faintness on standing, or light-headedness

These are not all the possible side effects of RECTIV. Call your doctor for medical advice about side effects. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

KEEP RECTIV OUT OF THE REACH OF CHILDREN.

To see full US Prescribing Information for RECTIV, please click here.

RECTIV is not suitable for children or adolescents under the age of 18 years because it has not been studied in this age group.
The information on this Web site is not intended or recommended as a substitute for medical advice, diagnosis, or treatment. Always seek the advice of your own physician or other qualified healthcare professional regarding any medical questions or conditions.

The product information provided in this site is intended only for residents of the United States. The product discussed herein may have different product labeling in different countries.

RE157-0113